We have an opening for a Rapid Response Laboratory Lead to oversee a High Throughput Antibody Production & Characterization Laboratory. You will be responsible for the development, implementation, and continuous optimization of automated high throughput protein production and screening platforms for the characterization of computationally designed therapeutic antibodies. You will also oversee day-to-day operations of the laboratory, assess performance metrics, and ensure programmatic objectives are met while maintaining safe and compliant operations. This position is in the Biosciences and Biotechnology Division.

You will

• Oversee stand up of the laboratory capability, including defining optimal production characteristics, optimizing high-throughput process, and troubleshooting.
• Supervise day-to-day laboratory operations and personnel producing and characterizing antibodies in support of broader effort to develop biological countermeasures.
• Provide technical direction and daily oversight of ~6 staff, including molecular biologists, microbiologists, and lab automation specialists.
• Monitor antibody production cycle processes (including molecular, transfection, purification, filtration) and down-stream characterization (including binding, affinity, and structural) to ensure analytic performance and compliance with Quality Assurance/Quality Control requirements.
• Collaborate with our team of diverse expertise, including biochemists, infectious disease biologists, engineers, and computational biologists, to develop and optimize antibody screening and selection strategies.
• Interact with external collaborators and/or contract research organizations to explore and/or execute commercial complementation toward program goals.
• Contribute to and actively participate in the development of integrated research programs to meet sponsor needs in multiple national security focus areas. Interact with senior project staff and management to influence programmatic decisions.
• Develop Standard Operating Procedures (SOPs) and maintenance records; ensure best practices for data reporting via LIMS.
• Participate in preparing for annual safety inspections and maintaining a safe laboratory environment in collaboration with EH&S.
• Perform other duties as assigned.